在Corydalis Rhizoma中,真菌微生物组的变异与不同的收集区域,加工方法和储存条件不同
Wenjun Jiang1, Mengyue Guo1, Jingsheng Yu1
1Institute of Medicinal Plant Development, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100193, China.
Food research international (Ottawa, Ont.)
|February 23, 2024
概括
在Corydalis Rhizoma (CR) 中的真菌污染令人担忧. 这项研究揭示了收集区域,加工和储存对CR的影响.
科学领域:
- 菌类学 菌类学是指菌类学.
- 微生物学 微生物学
- 药理学是指药理学,即药理学是指药理学.
背景情况:
- 科里达利斯树瘤 (Corydalis Rhizoma,简称CR),又称为延寿 (Yanhusuo),是一种传统的中国草药,用于缓解疼痛.
- 存在关于CR中真菌和真菌毒素污染的担忧,影响其安全性和有效性.
- 了解CR的真菌微生物群对于质量控制至关重要.
研究的目的:
- 在CR样本中调查真菌微生物组的组成和多样性.
- 评估地理来源,加工方法和储存条件对CR的真菌群落的影响.
- 为了识别CR中存在的潜在的毒性真菌.
主要方法:
- 用DNA元编码来分析真菌微生物组.
- 从四个草药市场采集了CR样本,并采用了两种加工方法.
- 随着时间的推移,冷藏和传统储存期间的真菌变异得到了监测.
主要成果:
- Aspergillus被确定为占主导地位的真菌属,萨帕特罗夫是最普遍的营养模式.
- 检测到六种潜在的毒性真菌,包括Aspergillus fumigatus和Penicillium citrinum.
- 根据收集区域,加工方法和储存条件 (温度和时间) 观察到真菌组成和多样性的显著差异.
结论:
- 收集区域,加工和储存显著影响Corydalis Rhizoma的真菌微生物组.
- 这些发现为制定控制整个CR产业链的真菌污染策略提供了基础.
- 这项研究强调了从来源到储存管理CR质量的重要性,以确保产品安全.
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