晚期泌尿癌中的前素-细菌与非细菌感染:前性队列研究
Hiroshi Yaegashi1, Kouji Izumi2, Ren Toriumi1
1Integrative Cancer Therapy and Urology, Graduate School of Medical Sciences, Kanazawa University, Kanazawa, Japan.
BMJ supportive & palliative care
|February 23, 2024
概括
在晚期泌尿癌患者中,血清公素有效区分细菌感染 (BI) 和非细菌感染 (NBI). 这种快速标志物有助于区分感染类型,当一般血液测试没有明确结果时.
科学领域:
- 在瘤学瘤学.
- 传染性疾病 传染性疾病
- 临床化学 临床化学
背景情况:
- 晚期癌症患者容易感染细菌感染 (BI).
- 区分BI与非细菌感染 (NBI) 在标准血液检测中具有挑战性.
- 准确的区分对于尿道癌症患者的适当治疗至关重要.
研究的目的:
- 为了评估血清甲酸水平,以区分BI与NBI.
- 评估前素在晚期泌尿癌的诊断效用.
- 为了与白细胞计数和C-反应蛋白进行比较.
主要方法:
- 对75名患有晚期泌尿道癌且出现发烧发作的患者进行前性研究.
- 对90次发烧发作进行分析,分为BI或NBI.
- 测量血清甲,白细胞计数和C反应蛋白.
主要成果:
- 在BI组中,血清甲酸水平显著更高 (p=0.0015).
- 白细胞计数和C反应蛋白在BI和NBI组之间没有显著差异.
- 在0.710.10的曲线下,普罗卡尔西托宁显示了接收器运行特征面积.
结论:
- 血清公素是一种有价值的标志物,可以在晚期泌尿癌中区分BI和NBI.
- 甲素提供了一个快速而负担得起的诊断工具.
- 这种标记物有助于临床医生在癌症患者的感染管理中.
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