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Updated: Jul 2, 2025

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在儿童重症病多年后,HPA轴基因内的DNA甲基化异常

Grégoire Coppens1, Ilse Vanhorebeek1, Fabian Güiza1

  • 1Clinical Division and Laboratory of Intensive Care Medicine, Department of Cellular and Molecular Medicine, KU Leuven, Herestraat 49, 3000, Leuven, Belgium.

Clinical epigenetics
|February 23, 2024
PubMed
概括

在儿科重症监护病房 (PICU) 接受治疗的儿童在下丘脑-垂体-上腺 (HPA) 轴基因中显示长期异常DNA甲基化,这与发育障碍有关. 葡萄糖皮质体治疗可能会加剧这些表观遗传变化,影响神经发育.

关键词:
孩子 孩子 孩子 孩子危急的疾病 危急的疾病通过DNA甲基化.葡萄糖皮质类固醇是什么?在HPA轴上.长期结果 长期结果

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