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Updated: Jul 2, 2025

Author Spotlight: Analyzing Bone Marrow Microenvironment in Murine Hematological Malignancies
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Author Spotlight: Analyzing Bone Marrow Microenvironment in Murine Hematological Malignancies

Published on: November 10, 2023

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骨髓质疏松性瘤临床前模型的演变

Alain Mina1, Steven Pavletic2, Peter D Aplan2,3

  • 1Myeloid Malignancies Program, Immune Deficiency Cellular Therapy Program, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA. alain.mina@nih.gov.

Leukemia
|February 24, 2024
PubMed
概括

开发有效的治疗神经骨髓质瘤 (MDS) 需要更好的临床前模型. 本综述探讨了当前和新兴的模型,以加快新型MDS疗法的发展.

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Mouse Models of Cancer Study02:43

Mouse Models of Cancer Study

Mice have long served as models for studying human biology and pathology because of their phylogenetic and physiological similarity with humans. They are also easy to maintain and breed in the laboratory, and hence, many inbred strains are now available for research. Studies on mice have contributed immeasurably to our understanding of cancer biology.
The development of transgenic, knockout, and knock-in mice has led to an exponential increase in their use as model organisms in research,...
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