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ApoE异型抑制了对抗炎症蛋白S100A9的粉样蛋白聚合

Shamasree Ghosh1, Shanmugam Tamilselvi1, Chloe Williams2

  • 1Department of Medical Biochemistry and Biophysics, Umeå University, SE-90187 Umeå, Sweden.

International journal of molecular sciences
|February 24, 2024
PubMed
概括

Apolipoprotein E (ApoE) 异型抑制了S100A9的聚合,这种蛋白质与阿尔茨海默病 (AD) 神经炎症有关. 这一发现表明,ApoE可能通过减少S100A9粉样蛋白形成来调节AD病理.

关键词:
阿尔茨海默氏症是阿尔茨海默氏症的一种疾病.在S100A9A9中使用.氨基化物 氨基化物阿波利波蛋白 E 是一种阿波利波蛋白.细胞毒性 细胞毒性纤维,纤维状的 纤维.抑制抑制抑制的抑制作用神经退行症的神经退行症神经炎症是一种神经炎症.这是一种亲炎症性炎症.

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