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Updated: Jul 2, 2025

An In Vitro Approach to Study Mitochondrial Dysfunction: A Cybrid Model
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人类ATP合成酶线粒体基因的变异:生物化学功能障碍,相关疾病和治疗方法

Valentina Del Dotto1, Francesco Musiani2, Alessandra Baracca1

  • 1Laboratory of Biochemistry and Mitochondrial Pathophysiology, Department of Biomedical and Neuromotor Sciences, University of Bologna, 40126 Bologna, Italy.

International journal of molecular sciences
|February 24, 2024
PubMed
概括

线粒体ATP合成酶基因MT-ATP6和MT-ATP8中的致病变体会导致衰弱性疾病. 本综述详细介绍了这些变体,它们的分子机制以及ATP合成酶缺乏症的新兴治疗策略.

关键词:
这是ATP合成酶.在ATP6 ATP6中.在ATP8 ATP8中.在F1Fo-ATPase建模中.线粒体中的线粒体.这就是 mt-DNA.突变是发生在突变中的突变.治疗疗法治疗疗法治疗疗法

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