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Updated: Jul 2, 2025

The Importance of Correct Protein Concentration for Kinetics and Affinity Determination in Structure-function Analysis
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The Importance of Correct Protein Concentration for Kinetics and Affinity Determination in Structure-function Analysis

Published on: March 17, 2010

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蛋白酶抑制剂复合物的实验和计算的抑制常数的相关性

Peter Goettig1,2, Xingchen Chen2, Jonathan M Harris2

  • 1Department of Pharmaceutical and Medicinal Chemistry, Institute of Pharmacy, Paracelsus Medical University, Strubergasse 21, 5020 Salzburg, Austria.

International journal of molecular sciences
|February 24, 2024
PubMed
概括

这项研究引入了一种计算方法来预测抑制剂的功效,与实验数据保持一致. 这种方法有助于发现各种蛋白质标的强效抑制剂,包括蛋白酶及其他.

关键词:
在SARS-CoV-2中,主要的蛋白酶是SARS-CoV-2.范·特·霍夫方程式解离常数是一种解离常数.免费的能源自由的能源.希鲁丁 (Hirudin) 是一个人.抑制常数是一种阻碍常数.蛋白酶抑制剂是一种蛋白酶抑制剂.太阳花试素抑制剂的使用

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