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COVID-19 流行病增加了儿童新发型一型糖尿病的发生率

Orit Blumenfeld¹, Mikhail Rozenshmidt¹, Idan Eini¹

¹Israel Center for Disease Control, Ministry of Health, Ramat-Gan 5262000, Israel.

Children (Basel, Switzerland)

|February 24, 2024

概括

在以色列,COVID-19流行病显著增加了儿童1型糖尿病 (T1D) 发病率,特别是在青春期前和青春期儿童中. 后来接种疫苗在青春期的群体中降低了T1D的发病率.

科学领域:

儿科儿科儿科
内分泌学在内分泌学.
流行病学流行病学

背景情况:

COVID-19大流行对儿童1型糖尿病 (T1D) 发病率的影响仍在争论中.
这项研究调查了以色列大流行之前和期间儿童T1D发病率的趋势.

研究的目的:

分析以色列0-17岁儿童新发型T1D的发病率.
为了比较大流行前 (1997-2019) 和大流行期间 (2020-2022) 的T1D病率.

主要方法:

利用了0-17岁儿童国家T1D注册表的数据.
在大流行前和大流行期间对新诊断的T1D病例进行比较.
分析的发病率按年龄组分层 (0-4,5-9,10-14,15-17).

主要成果:

总体T1D发病率从12.9/10^5显著上升到2020年的17.7/10^5和2021年的16.7/10^5,从12.9/10^5上升到17.7/10^5.
在这两年大流行期间,在5-9岁,10-14岁和15-17岁的年龄组中观察到显著增加.
0-4岁的年龄组仅在第二次大流行年 (2021) 显示出显著增加.
2022年的抗COVID-19疫苗接种与10-14岁和15-17岁年龄组的发病率下降相关.

结论:

COVID-19大流行与青春期前和青春期儿童中新发型T1D的显著增加有关.
抗COVID-19疫苗接种表明,仅在青春期年龄组内,T1D发病率显著降低.

关键词:

在 COVID-19 疫情中,孩子们的孩子们的孩子们的孩子们.流行病学流行病学发生率的发生率.公共卫生公共卫生.第1类糖尿病 1型糖尿病

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