凝血与心房动之间的关联
Saira Rafaqat1, Sanja Gluscevic2, Dimitrios Patoulias3
1Department of Zoology (Molecular Physiology), Lahore College for Women University, Lahore 54600, Punjab, Pakistan.
Biomedicines
|February 24, 2024
概括
凝血因子和标志物与心房动 (AF) 的发展有关. 本综述详细介绍了纤维素素,前列血和血小板激活如何对AF的病变产生产生贡献.
科学领域:
- 心血管医学 心血管医学
- 血液学 血液学 血液学
- 生物化学 生物化学
背景情况:
- 在科学文献中记录了许多凝血因子和标记物.
- 升高的凝血因子水平与现有和新的心房动 (AF) 诊断相关.
研究的目的:
- 总结凝血在心房动 (AF) 病变发生过程中的作用.
- 要突出参与AF发展的关键凝血元件.
主要方法:
- 文献综述总结了有关凝血和AF的现有研究.
- 特定的凝血因子和 AF 发病因子所涉及的标记物的鉴定和讨论.
主要成果:
- 凝血不规则是AF病变发生的重要因素.
- 关键因素包括纤维素,纤维素,前激素,血栓模块素,可溶性尿激酶等离子素激活体受体,·维勒布兰德因子,P-选择素,D-二聚体和等离子素激活体抑制剂-1.
- 血小板激活也是AF发病的关键因素.
结论:
- 凝血系统的失调是心房的发展的一个关键因素.
- 了解这些机制可以为未来的AF治疗策略提供信息.
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