三维结合性心室合指数-在扩展性心肌病症中的新型预后标记物
Aura Vîjîiac1, Alina Ioana Scărlătescu2, Ioana Gabriela Petre1,2
1Cardiology Department, Carol Davila University of Medicine and Pharmacy, 050474 Bucharest, Romania.
Biomedicines
|February 24, 2024
概括
包括综合指数 (CACI) 在内的心房合指数预测了扩张性心肌病 (DCM) 患者的不良事件. CACI提供了超越传统风险因素的增量预测价值,改善了结果预测.
科学领域:
- 心脏病学 心脏病学
- 心声回声扫描 (Echocardiography) 是一种心声回声扫描.
- 心血管成像 - 心血管成像
背景情况:
- 心房心室合是临床结果的新兴预测因素.
- 扩张性心肌病 (DCM) 是心力衰竭的一个重要原因.
研究的目的:
- 评估左侧 (LACI),右侧 (RACI) 和联合 (CACI) 心房合指数在DCM患者的预后作用.
- 评估CACI是否提供已确定的风险因素的增量预后信息.
主要方法:
- 121名DCM患者接受了全面的3D心声回声.
- 使用3D终端透析体积来计算LACI,RACI和CACI.
- 患者被跟踪主要的不良心血管事件.
主要成果:
- 缺陷的心房合指数与不良事件有关.
- CACI显示了最高的预测准确度 (AUC = 0.66,p = 0.003).
- LACI,RACI和CACI是独立的预测指标;CACI显示了相对于传统因素的增量值.
结论:
- 3D心声回声学衍生的CACI是DCM中不良事件的独立预测器.
- 在DCM中,CACI提高了预后评估,超出了传统的风险分层.
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