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肥胖对接受CABG的HFrEF患者短期手术结果的影响:一项回顾性多中心研究

Christian Jörg Rustenbach¹, Stefan Reichert¹, Christoph Salewski¹

¹Department of Thoracic and Cardiovascular Surgery, German Cardiac Competence Center, Eberhard-Karls-University, 72076 Tuebingen, Germany.

|February 24, 2024

概括

肥胖显著增加死亡率,急性损伤,心力衰竭患者的心脏衰竭患者的心脏衰竭患者经历冠状动脉旁路移植 (CABG). 个性化护理策略对于改善这一高风险肥胖人口的结果至关重要.

科学领域:

心脏病学心脏病学
外科手术的结果
肥胖问题研究研究

背景情况:

全球肥胖率的上升需要了解其对心血管健康的影响.
经过冠状动脉旁路移植 (CABG) 的心力衰竭减排分数 (HFrEF) 患者代表了一个高风险的手术群体.
肥胖对HFrEF患者短期手术结果的特定影响需要研究.

研究的目的:

调查肥胖对接受CABG的HFrEF患者短期外科结局的影响.
为了比较正常体重和肥胖的HFrEF患者进行CABG之间的结果.
在这个患者群体中确定与肥胖相关的特定风险.

主要方法:

在574名接受CABG (2017-2023) 的患者进行了回顾性多中心研究.
患者分为正常体重 (BMI < 25 kg/m2) 和肥胖 (BMI ≥ 30 kg/m2) 的两组.
分析包括人口统计,临床数据,手术内管理,术后结果和实验室结果,使用包括二进制逻辑回归在内的统计测试.

主要成果:

肥胖患者的死亡率更高 (6.96%与3.68%,p=0.049) 和年龄更小 (65.84与69.15岁,p=0.003).
肥胖群体对输血的需求增加,住院时间更长 (14 vs. 13天,p=0.041),通风时间更长 (16 vs. 13小时,p=0.049).
在肥胖患者中观察到急性损伤 (AKI) (17.72%对9.20%,p=0.048) 和妄 (p=0.016) 的发生率显著更高.

结论:

肥胖与接受CABG的HFrEF患者的短期手术结果明显恶化有关.
增加的风险包括死亡率,急性损伤和术后妄想.
个性化的术后护理和进一步定制的研究对于这种高风险的肥胖人口至关重要.

关键词:

根据CABG的规定.这就是HFrEFEF.这是OPCAB的OPCAB.心脏衰竭是因为心脏衰竭.低EF低EF低EF低EF低EF低EF 肥胖肥胖肥胖肥胖肥胖肥胖肥胖肥胖

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