莱科在患有肝脏疾病的受试者中的保护作用:NUTRIHEP研究
Rossella Donghia1, Angelo Campanella1, Caterina Bonfiglio1
1National Institute of Gastroenterology-IRCCS "Saverio de Bellis", 70013 Castellana Grotte, Italy.
Nutrients
|February 24, 2024
概括
番茄中的百合素 (LYC) 显示出对抗肝脏疾病的保护作用. 最佳的每日9.50毫克的摄入量可能会降低疾病风险,这表明它在未来的治疗中具有潜力.
科学领域:
- 营养科学 营养科学
- 肝病学 肝病学是一种肝病学.
- 公共卫生 公共卫生
背景情况:
- 肝脏疾病是全球日益关注的问题,通常与饮食有关.
- 富含蔬菜的饮食被认为有助于预防肝脏疾病.
- 这项研究调查了番茄中的烯 (LYC) 的保护潜力.
研究的目的:
- 探索从煮熟和新鲜西红中提取的烯 (LYC) 提取物对肝病的保护作用.
- 评估莱科在对抗肝脏病理方面的疗效.
- 评估烯作为治疗肝病的治疗剂的潜力.
主要方法:
- 利用了来自NUTRIHEP队列 (2005-2006) 和随访 (2014-2016) 的969名参与者的数据.
- 参与者根据肝脏状况被分为三组:非酒精性脂肪性肝病 (NAFLD),酒精性脂肪性肝病 (AFLD) 和一般性脂肪性肝病 (FLD).
主要成果:
- 红 (LYC) 消费显示出对抗肝病的统计学上显著的保护作用.
- 最佳摄入量为9.50毫克/天的LYC与降低风险相关 (RR=0.59,p=0.01).
- 相对降低风险 (RRR) 为0.40 (p=0.002),表明有显著的保护性益处.
结论:
- 这项研究支持了番茄衍生型烯 (LYC) 对抗肝病的人类保护作用.
- 这项研究为LYC在肝脏健康中的作用的有限文献做出了贡献.
- 莱科作为未来肝脏疾病治疗的补充剂显示出有前途的前景,潜在的禁忌较少.
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