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Updated: Jul 2, 2025

Assessment of Human Natural Killer Cell Events Driven by FcγRIIIa Engagement in the Presence of Therapeutic Antibodies
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NK细胞水平与多发性硬化症患者的疾病活性相关,这些患者接受了ocrelizumab/rituximab治疗

Simone Dal Bello1, Simone Lorenzut2, Emma Saccomano1

  • 1Clinical Neurology Unit, Santa Maria della Misericordia University Hospital, 33100 Udine, Italy.

Pharmaceuticals (Basel, Switzerland)
|February 24, 2024
PubMed
概括

像Ocrelizumab/Rituximab这样的抗CD20疗法在多发性硬化症 (MS) 患者中减少B细胞并增加NK细胞. 治疗后较低的NK细胞水平可能预测未来的MS疾病活性.

关键词:
在 NK 细胞中,NK 细胞是 NK 细胞.这就是Ocrelizumab.里图西马布 (Rituximab) 是一种药物.这是一种抗CD2020的药物.多发性硬化症多发性硬化症

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T Cell Types and Functions01:24

T Cell Types and Functions

When T cells with CD4 markers are activated, they give rise to two types of effector cells: helper T cells and regulatory T cells. Meanwhile, T cells with CD8 markers differentiate into effector cytotoxic T cells. The differentiation of CD4 T cells into helper T cell subsets, such as Th1, Th2, and Th17 cells, is dependent on the antigen type, antigen-presenting cell, and regulatory cytokines.
Th1 cells stimulate dendritic cells to express necessary co-stimulatory molecules on their surfaces for...
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