感染性内心炎在患有黄金葡萄球菌 (Staphylococcus aureus) 细菌病和骨和关节感染的患者中的患病率
Matthaios Papadimitriou-Olivgeris1,2, Benoit Guery1, Pierre Monney3
1Infectious Diseases Service, Lausanne University Hospital, University of Lausanne, 1011 Lausanne, Switzerland.
Microorganisms
|February 24, 2024
概括
传染性内心炎 (IE) 发生在27%的患有骨关节感染 (BJIs) 和黄金杆菌菌病的患者中. 在本地BJIs中,IE比在植入物相关感染中更常见.
科学领域:
- 传染性疾病 传染性疾病
- 心脏病学 心脏病学
- 整形外科 整形外科 整形外科
背景情况:
- 骨关节感染 (BJIs) 可能因系统性传播而复杂化,包括感染性内心炎 (IE).
- 黄金葡萄球菌是BJIs中常见的病原体,也是IE的常见原因.
- 患有BJIs的患者中IE的患病率,特别是区分原生和植入物相关的感染,需要进一步调查.
研究的目的:
- 为了评估感染性内心炎 (IE) 在患有骨关节感染 (BJIs) 和黄金杆菌菌菌病的患者中发生的情况.
- 为了比较IE在本地BJIs与骨科植入物相关感染 (OIAI) 的患病率.
主要方法:
- 2014年至2023年在洛桑大学医院进行的一项观察性研究.
- 纳入标准:涉及BJI,黄金葡萄球菌菌血症和心脏成像的情节.
- 对IE的诊断由内心炎专家团队定义.
主要成果:
- 在包括的384个发作中,IE在102个发作中被诊断出 (27%).
- 与OIAI (13%) 相比,本地BJIs (31%) 的IE患病率显著更高 (p < 0.001).
- 原生BJIs包括败血性关节炎,急性和慢性骨髓炎;OIAI包括假肢关节感染和骨质合成/脊髓炎感染.
结论:
- 在患有BJIs的患者中,黄金葡萄球菌细菌病与感染性内心炎的实质性风险有关.
- 与植入物相关感染患者相比,患有本地骨和关节感染的患者患IE的患病率要高得多.
- 这突显了心脏评估在患有黄金色杆菌病和本地BJIs的患者的重要性.
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