聚乙烯醇,用于制药3D打印的多功能辅料
Nadine Couți1, Alina Porfire1, Rareș Iovanov1
1Department of Pharmaceutical Technology and Biopharmacy, Faculty of Pharmacy, University of Medicine and Pharmacy "Iuliu Hatieganu", 400012 Cluj-Napoca, Romania.
Polymers
|February 24, 2024
概括
本综述探讨了用于3D打印制药的聚乙醇 (PVA),重点是化沉积建模 (FDM). 它强调了PVA.
科学领域:
- 制药技术 制药技术 制药技术
- 材料科学 是一种材料科学.
- 增材制造 增材制造是一种增材制造.
背景情况:
- 三维 (3D) 打印可以实现多种药物剂量形式,包括个性化药物.
- 选择合适的辅助剂对于3D打印技术至关重要.
- 聚合物是初级材料,聚乙醇 (PVA) 广泛用于化沉积建模 (FDM).
研究的目的:
- 审查3D打印剂型中制药级PVA的特性和应用.
- 专注于PVA在化沉积建模 (FDM) 技术中的利用.
- 为了证明克服制定和加工的挑战,以优化药物输送.
主要方法:
- 关于制药级PVA属性的文献综述.
- 分析PVA在各种3D打印技术中的应用,特别是FDM.
- 检查基于PVA的剂型的配方和加工策略.
主要成果:
- 制药级PVA具有适合3D打印的物理和化学特性.
- 通过FDM创建多种多样的剂量形式,PVA是多功能性的.
- 现有战略可以解决PVA的制定和处理挑战.
结论:
- 聚乙烯醇是3D打印制药剂型的关键聚合物,特别是使用FDM.
- 仔细的配方和加工使得使用PVA创建量身定制的药物输送系统成为可能.
- 使用PVA的3D打印为个性化医疗和先进的药物释放配置文件提供了显著的潜力.
相关概念视频
Plasticizers
Water-reducers, or plasticizers, are chemical admixtures used in concrete to improve strength and workability. These additives reduce the water-cement ratio without compromising workability, lower the cement content while maintaining the same workability, or increase workability to assist concrete placement in inaccessible areas.
Plasticizers function by using surface-active agents to create repulsive electrostatic forces between cement particles. This dispersion enhances the concrete's...
Plasticizers function by using surface-active agents to create repulsive electrostatic forces between cement particles. This dispersion enhances the concrete's...
Superplasticizers
Superplasticizers are advanced admixtures that enhance the workability of concrete by lowering the water content without compromising the strength of the material. These substances are highly effective water reducers, improving concrete flow, making it easier to work with, and enabling concrete to reach inaccessible areas or densely reinforced sections without mechanical vibration. The key components in superplasticizers are either sulfonated melamine or naphthalene formaldehyde condensates,...
Site-Targeted Drug Delivery Systems: Polymeric Carriers
Polymeric carriers enhance targeted drug delivery by increasing efficacy while minimizing off-target effects. These carriers comprise a biodegradable polymeric backbone integrated with functional elements that enable targeting, improve physicochemical properties, and regulate drug release.Targeting MechanismsThe targeting ability of polymeric carriers is mediated by a homing device, which is a molecular recognition component designed to selectively bind to specific tissues or cells. Monoclonal...


