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在患有多发性硬化症的患者中,COVID-19疫苗接种覆盖率和相关因素
Ignacio Hernández-García1,2, Joana Rodríguez-Montolio3, Monserrath Almeida-Zurita3
1Department of Preventive Medicine and Public Health, Lozano Blesa University Clinical Hospital of Zaragoza, Calle San Juan Bosco 15, 50009 Zaragoza, Spain.
Vaccines
|February 24, 2024
概括
多发性硬化症 (MS) 患者的COVID-19疫苗接种覆盖率达到90.3%的初始剂量,高于其他国家. 然而,强剂量摄入量下降,需要有针对性的策略,特别是在60岁以下的女性.
科学领域:
- 神经学 神经学
- 免疫学 免疫学 免疫学
- 公共卫生 公共卫生
背景情况:
- 多发性硬化症 (MS) 是一种慢性神经系统疾病.
- 对于脆弱人群,包括多发性硬化症患者,COVID-19疫苗接种至关重要.
- 了解MS患者的疫苗接种覆盖率和相关因素对于公共卫生战略至关重要.
研究的目的:
- 为了确定多发性硬化症 (MS) 患者的COVID-19疫苗接种范围.
- 在MS患者中确定与初级和辅助COVID-19疫苗接种相关的因素.
- 为改善这一群体疫苗接种率的策略提供信息.
主要方法:
- 从2017-2021年对359名多发性硬化患者进行了回顾性队列研究.
- 从专科和初级保健记录中收集的数据.
- 用于分析疫苗接种数据的双变量分析和多重逻辑回归模型.
主要成果:
- 90.3%的多发性硬化症患者接受了针对COVID-19的完整初级疫苗接种.
- 与初级疫苗接种相关的因素包括西班牙的出生和之前的流感疫苗接种.
- 强剂量覆盖率为39.3%,与男性性别,60岁以上,进展性MS类型和最近接种流感疫苗有关.
结论:
- 在MS患者中,COVID-19初级疫苗接种覆盖率很高,超过了国际水平.
- 观察到提升剂量摄入量的显著下降.
- 需要采取超出与流感疫苗联合使用的策略,以提高增强剂覆盖率,特别是在年轻女性中.
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