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在人类呼吸中实时测量CH₄使用一个紧的CH₄/CO₂传感器

Yueyu Lin¹, Dexter Manalili¹, Amir Khodabakhsh¹

¹Life Science Trace Detection Laboratory, Department of Analytical Chemistry and Chemometrics, Institute for Molecules and Materials, Radboud University, 6525 AJ Nijmegen, The Netherlands.

Sensors (Basel, Switzerland)

|February 24, 2024

概括

一个新的,便携式呼吸传感器准确地实时测量甲 (CH4) 和二氧化碳 (CO2). 这种非侵入性工具可以通过分析呼出的呼吸成分来帮助监测健康状况.

科学领域:

生物医学工程生物医学工程
分析化学分析化学
医学诊断医学诊断医学诊断

背景情况:

呼出的气息中甲 (CH4) 的升高表明某些健康状况.
非侵入性监测需要紧,负担得起和可携带的传感器.
同时测量CH4和二氧化碳 (CO2) 有助于确定端潮度.

研究的目的:

开发和验证一个紧的,便宜的,可携带的传感器,用于实时测量排出的甲 (CH4) 和二氧化碳 (CO2).
在CH4/CO2测量中解决和纠正水蒸气干扰.
通过呼吸分析来实现准确的,非侵入性的健康监测.

主要方法:

使用商用调节二极管激光吸收光谱 (TDLAS) 模块用于CH4和CO2检测.
开发并实施了对水蒸气干扰的实验性校正功能.
集成了一个定制的呼吸采样器,用于实时呼气分析.

主要成果:

开发的传感器准确地测量了呼出的气息中的实时CH4和CO2配置文件.
校正功能有效地减轻了水蒸气干扰.
在1.5秒的测量时间内,CH4的最低检测极限约为80ppbv,CO2的最低检测极限为700ppbv.

结论:

基于TDLAS的呼吸传感器能够准确,实时,非侵入性地监测呼出的CH4和CO2.
传感器的便携性和成本效益使其适用于广泛的健康诊断.
这项技术为早期发现和管理各种健康状况提供了一个有希望的途径.

关键词:

呼吸呼吸呼吸呼吸二氧化碳是二氧化碳的一种物质.纠正功能纠正功能纠正功能甲是一种甲.实时测量实时测量

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