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Updated: Jul 2, 2025

Assessing Changes in Volatile General Anesthetic Sensitivity of Mice after Local or Systemic Pharmacological Intervention
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在用propofol诱导全身麻醉时,remifentanil的血液动力学效应. 一个随机试验

Gunnar Helge Sjøen1,2,3, Ragnhild Sørum Falk4, Tor Hugo Hauge5

  • 1Department of Anaesthesiology, Fonna Hospital Trust, Haugesund, Norway.

Acta anaesthesiologica Scandinavica
|February 24, 2024
PubMed
概括

较高剂量的雷米芬坦尼尔在全身麻醉诱导过程中没有显著改变静脉压 (SAP). 这项研究发现,当Remifentanil与Propofol结合使用时,没有剂量依赖的血液动力学影响.

关键词:
血液动力学 血液动力学药物的生理效应药物的生理效应.普罗波福尔 (Propofol) 是一种雷米芬坦尼尔的使用方法

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Intravenous anesthetics are drugs administered parenterally to induce anesthesia or sedation. Propofol is a widely used agent formulated as a 1% emulsion in soybean oil, glycerol, and egg phosphatide. It induces rapid anesthesia primarily due to its rapid distribution from the bloodstream to target tissues and is metabolized in the liver. However, it can cause significant pain on injection and hypertriglyceridemia. Fospropofol, a water-based prodrug of propofol, lacks these adverse effects.
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