使用公开可用的人工智能系统对输血后不良事件进行分类
Mark K Fung1, James P AuBuchon2, Laura D Stephens3
1Department of Pathology and Laboratory Medicine, University of Vermont Larner College of Medicine, Burlington, Vermont, USA.
Transfusion
|February 24, 2024
概括
生成型人工智能 (AI) 在分类输血反应方面表现出可变的准确性,正确识别了一些,但错过了其他一些. 虽然人工智能可以帮助识别潜在反应,但建议对当前的临床分类保持谨慎.
科学领域:
- 医疗信息学 医疗信息学
- 医疗保健中的人工智能
- 输血医学 输血医学
背景情况:
- 对输血反应的准确分类对于患者护理,供体管理和血液监测至关重要.
- 生成型人工智能 (AI) 提供了在医疗保健机构诊断援助的潜力.
研究的目的:
- 将生成AI系统的诊断准确性与输血医学 (TM) 专家在分类输血反应方面进行比较.
- 评估AI的诊断能力,评估严重程度,并使用既定标准确定输血反应的归因性.
主要方法:
- 一个人工智能系统评估了36个输血反应案例场景.
- 人工智能反应与专家小组的分类和先前的TM专家评估进行了比较.
- 人工智能表现与TM专家进行了基准测试,使用TrDDx基于网络的算法来处理具有挑战性的案例.
主要成果:
- 根据输血反应类别,AI的准确性差异很大,在一些方面表现出色 (例如,TACO,TRALI),但在其他方面失败 (例如,DSTR).
- 整体AI准确率为48.7%,而TM专家的准确率为72.1% (p=0.005).
- 人工智能响应经常使用非标准的术语,缺乏严重性和归因性评估.
结论:
- 生成型人工智能可以帮助临床医生识别错过的输血反应类别.
- 目前的AI输出需要在临床应用之前仔细考虑和验证输血反应分类.
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