2型糖尿病患者的HbA1c和BMI趋势:一项日本基于索赔的研究
Kazuo Hara1, Tetsuaki Hirase2, Swathi Pathadka3
1Department of Medicine, Jichi Medical University Saitama Medical Center, Saitama, Japan.
概括
超过一半的日本成年人患有2型糖尿病 (T2D) 和肥胖,血糖控制不佳 (HbA1c ≥7%). 体重管理对于改善血糖水平至关重要,特别是在年轻的肥胖T2D患者中.
科学领域:
- 内分泌学 在内分泌学.
- 代谢疾病 代谢疾病
- 公共卫生 公共卫生
背景情况:
- 日本肥胖率的上升与血糖控制不佳和2型糖尿病 (T2D) 风险增加有关.
- 中部肥胖是T2D的重要危险因素.
- 了解日本T2D患者的肥胖指标和血糖控制之间的相互作用至关重要.
研究的目的:
- 描述日本2型糖尿病患者的糖化血红蛋白 (HbA1c),体重指数 (BMI) 和腰围的当前趋势.
- 分析不同年龄和性别群体中肥胖指标和血糖控制之间的关系.
- 为了确定T2D队列中表现出低血糖控制的特定人群.
主要方法:
- 使用日本医疗数据中心索赔数据库进行回顾性,横截面研究.
- 纳入标准:患有T2D并记录HbA1c和BMI或腰围的人.
- 分析了2017年1月至2021年12月的五个年度队列,检查了BMI类别和中心肥胖症的HbA1c趋势,按性别和年龄分层.
主要成果:
- 分析了超过106,000名2型糖尿病患者,其中大多数人属于肥胖类I和II.
- 较高的BMI类别与较高的平均HbA1c水平相关;肥胖类I-IV中的50%以上的HbA1c≥7%.
- 2017-2021年间,BMI和腰围在18-44岁的年龄组中增加. 超过50%的T2D患者患有中心肥胖或更高的BMI类别,特别是18-44岁的患者,HbA1c≥7%.
结论:
- 很大一部分 (超过50%) 的日本T2D患者患有肥胖 (I-IV类) 或中心肥胖症,血糖控制不佳 (HbA1c ≥7%).
- 患有T2D和肥胖的18-44岁年龄组显示,血糖控制不良的患病率特别高.
- 有效的体重管理策略对于改善T2D和肥胖的年轻日本人的血糖控制至关重要.
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