孕产妇和新生儿的皮质醇和catecholamines在整个阴道安乐死和C-section在狗
Renata Azevedo de Abreu1, Letícia Lima de Almeida1, Maíra Morales de Brito1
1Department of Animal Reproduction, School of Veterinary Medicine and Animal Science, University of São Paulo, São Paulo, Brazil.
Domestic animal endocrinology
|February 24, 2024
概括
剖腹产导致更大的孕产妇压力,而阴道分娩导致更高的新生儿压力,帮助小狗的适应. 这项研究比较了经历了不同类型的分娩的狗的周周皮质醇和甲醇胺.
科学领域:
- 兽医医学 兽医医学 兽医医学
- 生殖生理学 生殖生理学
- 新生儿适应新生儿适应
背景情况:
- 胎儿皮质醇通过甲醇胺释放影响新生儿的适应性反应.
- 在母狗和新生儿中,围产部分皮质醇和甲醇胺之间的关系尚不清楚.
- 了解这些荷尔蒙变化对于评估母婴在狗分娩期间的母亲和新生儿福祉至关重要.
研究的目的:
- 为了比较不同产科条件下 (阴道安乐死与选择性剖腹产) 围产母狗和新生儿的血清上腺素,上腺素和皮质醇水平.
- 为了评估羊水皮质醇度与交付类型的关系.
- 评估分娩方式对母亲和新生儿应激反应的影响.
主要方法:
- 从20只母狗及其新生儿 (n=37) 收集了血清样本,分娩前,分娩内,分娩后和分娩后1小时.
- 新生儿血液样本是在出生时,30分钟,60分钟,12小时和分娩后24小时收集的.
- 测量了皮质醇,上腺素和上腺素水平,以及产时羊水皮质醇度.
主要成果:
- 与阴道分娩相比,剖腹产导致在手术期间和之后的母体诺亚上腺素和皮质醇水平更高.
- 在剖腹产犬中,母体皮质醇从产后逐渐增加,而新生儿皮质醇保持稳定.
- 阴道分娩的小狗在出生和30分钟后表现出更高的皮质醇度,在阴道安乐死病例中观察到更高的胎液皮质醇.
结论:
- 选择性剖腹产在手术过程中和手术后立即引起了母亲的重大压力.
- 阴道分娩对新生儿来说是一个更具生理压力的情况,可能会在过渡期提高他们的适应能力.
- 这些发现突出了与狗的不同分娩方法相关的不同孕产妇和新生儿压力概况.
更多相关视频
09:49Assessment of Perigenital Sensitivity and Prostatic Mast Cell Activation in a Mouse Model of Neonatal Maternal Separation
Published on: August 13, 2015
9.3K
06:39Using a Murine Model of Psychosocial Stress in Pregnancy as a Translationally Relevant Paradigm for Psychiatric Disorders in Mothers and Infants
Published on: June 13, 2021
3.1K
相关概念视频
Teratogenicity
The ability of a drug to produce structural deformations and functional abnormalities in the developing embryo or the fetus is called teratogenicity, and the drug producing this effect is known as a teratogen. Teratogenic effects include stillbirth, miscarriage, intrauterine growth restriction, and neurocognitive delay. A teratogen may affect the embryo at different stages of development, which is important in determining the type and extent of the damage. During blastocyst formation, the early...
Development of the Oral Microbiota
The establishment of the oral microbiome begins before birth, challenging the long-held belief that the fetal oral cavity is sterile. The presence of oral microbes such as Streptococcus and Fusobacterium in amniotic fluid suggests that microbial exposure may occur in utero, potentially through translocation from the maternal oral or gastrointestinal tract. This early colonization primes the neonatal immune system and sets the stage for subsequent microbial succession. Maternal health,...
