U-PASS:一个以不确定性为导向的深度学习管道,用于自动化睡眠分期
Elisabeth R M Heremans1, Nabeel Seedat2, Bertien Buyse3
1KU Leuven, Department of Electrical Engineering (ESAT), STADIUS Center for Dynamical Systems, Signal Processing and Data Analytics, Kasteelpark Arenberg 10, B-3001 Leuven, Belgium.
Computers in biology and medicine
|February 24, 2024
概括
这项研究引入了U-PASS,一个以人为中心的机器学习管道,该管道估计了不确定性,以提高临床AI可靠性. U-PASS与专家合作,在睡眠呼吸暂停的老年患者的睡眠分期中实现了85%的准确性.
科学领域:
- 临床机器学习 临床机器学习
- 医疗保健中的人工智能
- 不确定性定量化 不确定性定量化
背景情况:
- 机器学习 (ML) 越来越多地用于关键的医疗保健应用.
- 确保医疗保健中的ML系统的安全性和可靠性至关重要.
- 不确定性估计是确定可靠预测和降低风险的关键.
研究的目的:
- 推出U-PASS,一个以人为中心的ML管道用于临床应用.
- 在整个ML生命周期 (数据采集,培训,部署) 中整合不确定性估计.
- 通过专家合作和不确定性沟通,提高ML可靠性.
主要方法:
- U-PASS采用两步培训过程:受监督的预培训和半受监督的微调.
- 在所有阶段估计不确定性,指导数据优化和专家反.
- 管道将不确定的预测推迟到临床专家进行审查.
主要成果:
- U-PASS用于老年睡眠呼吸暂停患者的睡眠分期.
- 在管道的所有阶段,性能系统地得到改善.
- 实现了85%的专家级准确性,比基线 (75%) 增加了10%.
- 将不确定的样本推迟给专家带来了最显著的业绩增长.
结论:
- U-PASS展示了一种有希望的方法,用于将不确定性估计整合到临床ML中.
- 该管道提高了ML的可靠性,并促进了与医疗保健专业人员的合作.
- 这种方法有可能在临床环境中释放人工智能的全部功能.
相关概念视频
Stages of Sleep
192
Sleep progresses through distinct stages, each characterized by specific brain wave patterns and physiological responses ranging from wakefulness to stages of non-rapid eye movement, known as non-REM, to rapid eye movement, referred to as REM. Understanding these stages helps in recognizing how sleep supports various bodily and cognitive functions.
Before sleep begins, in wakefulness, the brain exhibits primarily beta waves, which are high in frequency and low in amplitude, indicating alertness...
Before sleep begins, in wakefulness, the brain exhibits primarily beta waves, which are high in frequency and low in amplitude, indicating alertness...
192
Sleep-Wake Cycles
1.3K
Sleep is an essential physiological process vital to maintaining overall well-being. The reticular activating system (RAS), a network of neurons in the brainstem, regulates wakefulness and sleep. While it may seem passive, sleep consists of distinct cycles, each with its unique characteristics and functions. Two key sleep phases are non-rapid eye movement (NREM) and rapid eye movement (REM).
NREM Sleep
NREM sleep comprises four progressive stages that seamlessly merge:
NREM Sleep
NREM sleep comprises four progressive stages that seamlessly merge:
1.3K
Stages of General Anesthesia
444
Various sedation levels offer significant advantages in facilitating procedural interventions for patients undergoing medical or invasive surgical procedures. These levels span from anxiolysis to general anesthesia, providing a spectrum of sedative effects to cater to specific patient needs. Anxiolysis reduces anxiety and is achieved through minimal sedation, enabling patients to remain awake and responsive while feeling more at ease during the procedure. This level can benefit minor...
444
Management of Insomnia
248
The sleep cycle, an integral part of human health, consists of several stages with distinct characteristics and functions. It begins with a transition from wakefulness to sleep, known as the light sleep phase, followed by the restorative deep sleep phase, essential for physical recovery and growth. The cycle concludes with the Rapid Eye Movement (REM) phase, characterized by high brain activity and vivid dreaming. Insomnia, a prevalent sleep disorder, involves difficulty falling asleep, staying...
248


