肠道微生物的共代谢物2-甲基甲基卡尼丁通过与整合素α2β1结合和激活而加剧血栓形成

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Kan Huang1, Zilun Li2, Xi He3

  • 1Guangdong Provincial Key Laboratory of Malignant Tumor Epigenetics and Gene Regulation, Guangdong-Hong Kong Joint Laboratory for RNA Medicine, Medical Research Center, Sun Yat-Sen Memorial Hospital, Sun Yat-Sen University, Guangzhou, Guangdong 510120, China; Nanhai Translational Innovation Center of Precision Immunology, Sun Yat-Sen Memorial Hospital, Foshan, Guangdong 528200, China; Division of Vascular Surgery, The First Affiliated Hospital of Sun Yat-Sen University, Guangzhou, Guangdong 510080, China; National-Guangdong Joint Engineering Laboratory for Diagnosis and Treatment of Vascular Diseases, The First Affiliated Hospital of Sun Yat-Sen University, Guangzhou, Guangdong 510080, China.

Cell metabolism
|February 24, 2024
PubMed
概括

一种新发现的代谢物,二甲基丁二甲基 (2MBC),通过增强血小板激活来促进血栓形成. 肠道微生物群对2MBC水平有影响,这表明失生症和心血管事件之间存在联系.

关键词:
这是一种二甲基基尼丁二甲基基尼丁.BTT 303333 的时间.肠道微生物代谢物的代谢物.整体中的α2β1β1血小板的高反应性.血栓形成的原因是血栓形成.

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