后重症监护综合征 - 儿科 (PICS-p) 纵向队列研究的设计和理由
Martha A Q Curley1,2, R Scott Watson3,4, Elizabeth Y Killien3,4
1School of Nursing, University of Pennsylvania, Philadelphia, Pennsylvania, USA curley@nursing.upenn.edu.
BMJ open
|February 24, 2024
概括
这项研究跟踪了儿童重症监护后的儿童,确定了幸存者及其家人的长期身体,认知和情感挑战,以改善未来的护理.
科学领域:
- 儿科重症监护医药 儿科重症监护医药
- 纵向队列研究是指纵向队列研究.
- 儿童健康结果的结果.
背景情况:
- 儿科重症监护室 (PICU) 的死亡率正在下降,重点转移到幸存者的发病率上.
- 关于PICU后儿童和家庭的身体,认知,情感和社会后果的理解有限.
- 在PICU幸存者中,康复的轨迹和发病风险因素在很大程度上是未知的.
研究的目的:
- 评估儿童和家庭在PICU退院后2年的结果.
- 确定与PICU幸存者的受损结果相关的儿童和临床因素.
- 描述儿科重症对儿童及其家人的持续影响.
主要方法:
- 纵向队列研究招收了30个美国PICU的750名儿童.
- 500名病例参与者 (≥3天重症监护) 和250名对照参与者 (≤1晚 PICU) 的比较.
- 对儿童,父母和兄弟姐妹进行多次时间点调查,评估生活质量,功能,认知和情绪健康.
主要成果:
- 研究正在进行中; 结果正在等待.
- 分析将比较病例和对照组之间的结果和恢复轨迹.
- 将确定导致不良结果的风险因素以及对父母/兄弟姐妹的影响.
结论:
- 描述长期结果对于为儿科重症幸存者开发干预措施至关重要.
- 了解PICU后挑战的全部范围将指导支持性护理策略.
- 发现的传播旨在优化严重疾病影响的儿童和家庭的结果.
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