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Updated: Jul 2, 2025

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表达FFAR2的骨髓系衍生抑制细胞驱动癌症免疫逃生

Zeda Zhao1, Juliang Qin1, Ying Qian1

  • 1Shanghai Frontiers Science Center of Genome Editing and Cell Therapy, Shanghai Key Laboratory of Regulatory Biology and School of Life Sciences, Institute of Biomedical Sciences and School of Life Sciences, East China Normal University, 500 Dongchuan Road, Shanghai, 200241, China.

Journal of hematology & oncology
|February 24, 2024
PubMed
概括

酸通过FFAR2.2激活骨髓衍生抑制细胞 (MDSCs) 来促进癌症免疫逃避. 针对这一轴可以逆转免疫抑制,改善癌症免疫治疗结果.

关键词:
在FFAR2的FFAR2免疫逃逸是一种免疫逃避.免疫治疗是一种免疫疗法.在MDSCs中.在SCFAs中,SCFAs是最重要的.

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