患有2型糖尿病的成年人中膜过的患病率和危险因素:基于人口的研究
Domenico Tricò1, Gian Paolo Fadini2, Mario Luca Morieri2
1Department of Clinical and Experimental Medicine, University of Pisa, Pisa, Italy.
Diabetes/metabolism research and reviews
|February 25, 2024
概括
淋巴细胞过,糖尿病病的早期迹象,影响高达3.4%的2型糖尿病患者. 它的流行与代谢风险因素的低最佳控制有关,强调需要更好的管理.
科学领域:
- 腎臟病學 (nephrology) 是一種醫學專業.
- 内分泌学 在内分泌学.
- 流行病学 流行病学
背景情况:
- 淋巴细胞过是一种糖尿病病的早期指标.
- 它预测了2型糖尿病 (T2D) 患者的不良脏和心血管结果.
研究的目的:
- 确定当代,基于人群的T2D患者队列中球过的流行率.
- 为了确定与膜过相关的危险因素.
主要方法:
- 分析了在意大利 (2021-2022) 接受专家护理的202,068名成年T2D患者的队列.
- 从75家糖尿病诊所的电子病历中提取数据.
- 淋巴细胞过被定义为估计的淋巴细胞过率>120mL/min/1.73m2.
主要成果:
- 在0.6%的参与者 (1262人) 中发现了淋巴细胞过.
- 患病率在各中心 (0%-3.4%) 有显著差异,与中心水平的年龄,HbA1c,BMI和LDL胆固醇相关.
- 过率较高 (>0.8%) 的中心有更多的男性,年龄较小,BMI较低,但有更多的白蛋白尿和较差的代谢控制.
结论:
- 在目前接受专家护理的T2D患者中,最多有3.4%的患者存在明确的淋巴细胞过.
- 患病率因中心而异,并且随着代谢风险因素的低最佳控制而增加.
- 改善对代谢风险因素的管理对于减轻健康负面影响至关重要.
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