分段重复驱动主要作物病原体中辅助区域的演变
Anouk C van Westerhoven1,2, Carolina Aguilera-Galvez1, Giuliana Nakasato-Tagami1
1Laboratory of Phytopathology, Wageningen University, Droevendaalsesteeg 1, 6708 PB, Wageningen, the Netherlands.
The New phytologist
|February 25, 2024
概括
最近的细分重复推动了Fusarium oxysporum中辅助区域 (AR) 的演变. 这些AR有助于香枯病原体的毒性,尽管感染同一宿主的菌株之间存在很高的多样性.
科学领域:
- 植物病理学 植物病理学
- 基因组学就是基因组学.
- 进化生物学 进化生物学
背景情况:
- 像Fusarium oxysporum这样的致病真菌拥有分隔的基因组,附属区域 (AR) 编码毒性因子.
- 水平转移的ARs可以改变病原体的病原性和宿主范围.
- 了解感染同一宿主菌株的AR演变对于疾病管理至关重要.
研究的目的:
- 研究导致香枯的Fusarium oxysporum菌株附属区域 (AR) 的多样性和演变.
- 确定推动这些病原体AR进化的基因组机制.
主要方法:
- 对69种不同的Fusarium oxysporum菌株进行泛基因组分析.
- 附属区域的比较基因组分析.
- 对细分重复事件的调查.
主要成果:
- 感染同一香品种的F. oxysporum菌株的辅助区域非常多样化,没有共享的基因组区域或在植物诱导的效应因子中被确定.
- 分段重复,特别是最近在辅助染色体上的重复,推动了ARs的扩张和进化.
- 这些ARs有助于香枯病原体中毒性的演变.
结论:
- 最近广泛的细分重复是Fusarium oxysporum附属区域演化的关键驱动因素.
- 这种进化机制有助于香枯病原体的毒性.
- 即使在感染同一宿主的菌株内,ARs的高度多样性也凸显了病原体进化的动态性质.
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