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Updated: Jul 2, 2025

A Reporter Assay to Analyze Intronic microRNA Maturation in Mammalian Cells
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A Reporter Assay to Analyze Intronic microRNA Maturation in Mammalian Cells

Published on: June 16, 2022

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由HnRNPR介导的UPF3BmRNA剪接驱动肝细胞癌转移

Hong Wang1, Dong Qian2, Jiabei Wang3

  • 1Anhui Province Key Laboratory of Hepatopancreatobiliary Surgery, Anhui Provincial Clinical Research Center for Hepatobiliary Diseases, The First Affiliated Hospital of USTC, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei, Anhui, China; Department of Radiation Oncology, The First Affiliated Hospital of USTC, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei, Anhui, China.

Journal of advanced research
|February 25, 2024
PubMed
概括

异常的替代拼接驱动肝细胞癌 (HCC) 转移. 这项研究揭示了UPF3B-S通过降解CDH1mRNA和激活YAP1-Hippo信号来促进HCC入侵,这表明UPF3B-S是潜在的生物标志物.

关键词:
另一个替代拼接.肝细胞癌是肝细胞癌.这是HnRNPR.侵袭和转移的发生.在UPF3B-S中,可以使用UPF3B-S.

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