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内核的变化会影响印米他素封装的聚合物微粒的药理动力学

Shugo Yamashita1, Karen Azuma1, Yuka Tanaka1

  • 1Department of Pharmacokinetics, Faculty of Pharmaceutical Sciences, Doshisha Women's College of Liberal Arts, Kyotanabe, Kyoto 610-0395, Japan.

International journal of pharmaceutics
|February 25, 2024
PubMed
概括

疏水性离子配对 (HIP) 菌株改善了药物保留. 修改内核HIP模式改变了细胞结构,影响了药物释放和血液保留,为药物输送提供了新的策略.

关键词:
疏水离子离子配对纳米粒子与蛋白质相互作用药物动力学 药物动力学聚合物的微粒.

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