复发性周围假肢关节感染:诊断,治疗和结果
Christopher F Deans1, Beau J Kildow1, Kevin L Garvin1
1Department of Orthopaedic Surgery and Rehabilitation, University of Nebraska Medical Center, 985640 Nebraska Medical Center, Omaha, NE 68198, USA.
The Orthopedic clinics of North America
|February 25, 2024
概括
周围假肢关节感染 (PJI) 是关节置换手术后的一个常见并发症. 优化最初的2阶段修复手术对于预防重复感染和改善患者的治疗结果至关重要.
科学领域:
- 整形外科手术 整形外科手术
- 传染性疾病 传染性疾病
- 生物医学工程 生物医学工程
背景情况:
- 周围假肢关节感染 (PJI) 是全面关节整形术后的一个重大并发症.
- 在管理方面,PJI带来了巨大的挑战,导致发病率,死亡率和医疗保健成本增加.
- 慢性PJI病例通常表现为治疗失败,重复感染涉及多微生物或多药物耐药生物.
研究的目的:
- 为了强调优化对周围假肢关节感染的初始2阶段修复手术的关键重要性.
- 强调在管理慢性PJI方面需要一个全面的,以团队为基础的战略.
- 要强调成功的指数程序在防止后续管理失败中的作用.
主要方法:
- 临床文献和围围假肢关节感染治疗指南的综述.
- 分析导致两阶段修订协议失败的因素.
- 在手术部位感染管理中强调多学科团队合作.
主要成果:
- 慢性PJI的两阶段治疗失败率特别高.
- 复发性感染经常涉及复杂的微生物特征,包括耐药菌株.
- 成功的初始两阶段修复手术对于长期的结果至关重要.
结论:
- 优化指数二阶段修订的成功是防止未来PJI复发的最有效策略.
- 一个强大的,以团队为基础的方法对于成功管理慢性PJI至关重要.
- 在初始治疗中解决挑战可以减轻重复感染的重大负担.
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