西方国家胃癌查:呼吁采取行动
Fabio Farinati1, Filippo Pelizzaro1
1Department of Surgery, Oncology and Gastroenterology, University of Padova, Via Giustiniani 2, Padova 35128, Italy; Gastroenterology Unit, Azienda Ospedale-Università di Padova, Via Giustiniani 2, Padova 35128, Italy.
概括
胃癌预防策略,包括 Helicobacter pylori 根除和毒素测试,至关重要. 实施这些措施,特别是在西方国家,可以改善患者的治疗结果,降低死亡率.
科学领域:
- 胃肠道学和瘤学
- 预防医学 预防医学
背景情况:
- 胃癌仍然是一个重要的全球健康问题,预后不佳,特别是在西方国家.
- 杆菌感染是主要的危险因素,被列为致癌物,其根除是初级预防的关键.
- 一个癌前级联络,包括胃缩和肠道转化,先于胃非心脏腺癌.
研究的目的:
- 审查胃癌的初级和二级预防措施.
- 讨论在西方国家实施胃癌查的必要性.
- 为临床使用提出一个实际的查算法.
主要方法:
- 审查关于预防胃癌的现有文献.
- 通过消除Helicobacter pylori的初级预防的分析.
- 评估二次预防使用pepsinogen水平用于内镜转诊.
- 讨论东亚与西方国家的选活动采用情况.
主要成果:
- 通过根除H. pylori,可以实现初级预防.
- 非侵入性素检测有助于识别需要上肠道内镜的人.
- 有效的查和监测方法存在,但在西方国家未得到充分利用.
- 日本和韩国等东亚国家已经实施了国家查计划.
结论:
- 胃癌查和监测对于早期检测和改善结果至关重要.
- 西方国家显然需要采用和调整胃癌查策略.
- 一个简单的查算法可以促进临床应用和加强预防工作.
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