荷兰的阴茎癌护理:发病率增加,集中化,生存率提高
Manon T A Vreeburg1, Hielke-Martijn de Vries1, Vincent van der Noort2
1Department of Urology, The Netherlands Cancer Institute-Antoni van Leeuwenhoek Hospital, Amsterdam, The Netherlands.
BJU international
|February 25, 2024
概括
阴茎状细胞癌 (PSCC) 的发病率在荷兰正在上升. 在国家中心集中医疗改善了生存率,即使是晚期病例,强调了PSCC专业治疗的好处.
科学领域:
- 在瘤学瘤学.
- 泌尿器科 泌尿器科 泌尿器科 泌尿器科
- 癌症流行病学 癌症流行病学
背景情况:
- 阴茎状细胞癌 (PSCC) 是一种罕见的恶性瘤.
- 对于PSCC的发病率和治疗集中化的趋势尚未确立.
- 集中护理模式可能会影响罕见癌症的生存结果.
研究的目的:
- 评估30年来荷兰PSCC的发病率和集中趋势.
- 评估PSCC护理集中化对患者存活率的影响.
- 为了确定PSCC患者的生存预测因素.
主要方法:
- 利用了来自荷兰癌症注册 (1990-2020) 的数据.
- 计算了年龄标准化的发病率和相对生存概率.
- 采用多变量考克斯回归来分析生存预测因素.
主要成果:
- 从1990年到2020年,PSCC的发病率显著增加.
- 在荷兰癌症研究所 (NCI) 观察到,PSCC护理的集中化趋势强烈.
- 与区域中心 (76%) 相比,在NCI治疗的患者的5年相对存活率 (86%) 显着更高,即使患有较高的T和N阶段疾病.
- 集中治疗与改善的生存率有关,独立于其他预后因素.
结论:
- 荷兰的PSCC发病率一直在增加.
- 在国家专业知识中心集中PSCC护理导致了更好的生存结果.
- 专业护理模式对于优化PSCC等罕见癌症的治疗结果至关重要.
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