在日本一般人口中,腹周和高尿血病发病率之间的关系
Kazumi Kawano1, Tamami Ueno1,2, Toshiki Maeda1
1Department of Preventive Medicine and Public Health, Fukuoka University, 7-45-1 Nanakuma, Jonan-ku, Fukuoka City, Japan.
Scientific reports
|February 25, 2024
概括
更大的腰围与男性和女性患高尿路血症的风险更高有关. 这项研究强调腰部尺寸是日本一般人口中高尿路血症发病率的关键指标.
科学领域:
- 代谢健康 代谢健康
- 流行病学 流行病学
- 公共卫生 公共卫生
背景情况:
- 尿酸过高的特征是高尿酸水平,这是一种日益严重的公共卫生问题.
- 腹部肥胖,表现为腰围增加,是代谢障碍的已知危险因素.
- 在日本一般人群中,腰围和高尿血病发病率之间的特定关系需要进一步澄清.
研究的目的:
- 为了研究腰围和高尿血的发生率之间的关联.
- 单独分析日本一般人口中男性和女性的这种关系.
主要方法:
- 一项以人口为基础的纵向研究是使用日本伊基市年度健康检查数据进行的.
- 在基线没有高尿素血症的5,567名参与者根据腰围被分类为三分之一.
- 考克斯的比例危险模型被用来评估腰围和发生性尿液高血症 (尿酸> 416 μmol/L) 之间的关系.
主要成果:
- 在随访期间,697名参与者患有高尿路血症.
- 在男性 (P<0.001) 和女性 (P=0.001) 两种情况下都观察到高腰围三角形的高尿路血症发病率增加的显著趋势.
- 在对两性潜在混因素进行调整后,这些关联仍然显著.
结论:
- 腰围的增加是男性和女性随后发展高尿路血的重要危险因素.
- 腰围作为一个有价值的指标,用于预测在一般人群中高尿血风险.
- 专注于体重管理,特别是腹部肥胖的公共卫生策略可能有助于降低超尿血病的发生率.
相关概念视频
Genome-wide Association Studies-GWAS
13.4K
Genome-wide association studies or GWAS are used to identify whether common SNPs are associated with certain diseases. Suppose specific SNPs are more frequently observed in individuals with a particular disease than those without the disease. In that case, those SNPs are said to be associated with the disease. Chi-square analysis is performed to check the probability of the allele likely to be associated with the disease.
GWAS does not require the identification of the target gene involved in...
GWAS does not require the identification of the target gene involved in...
13.4K
Cholesterol: Significance and Regulation
544
Although not a source of energy, cholesterol plays a significant role as a foundational structure for bile salts, steroid hormones, and vitamin D, as well as being a crucial component of plasma membranes. Approximately 15% of blood cholesterol is derived from our diet, with the remainder synthesized from acetyl CoA by the liver and intestines. Cholesterol is eliminated from the body through its conversion into bile salts, which are eventually discarded in the feces.
Considering cholesterol and...
Considering cholesterol and...
544
Peptic Ulcer Disease I: Introduction
168
Peptic Ulcer Disease (PUD) is characterized by mucosal excavation in the esophagus, stomach, pylorus, or duodenum. It can manifest as acute or chronic based on the extent and duration of mucosal involvement.
An acute ulcer, marked by superficial erosion and minimal inflammation, swiftly resolves upon identifying and addressing the underlying cause. In contrast, a chronic ulcer persists, potentially eroding through the muscular wall and forming fibrous tissue.
Peptic ulcers can also be...
An acute ulcer, marked by superficial erosion and minimal inflammation, swiftly resolves upon identifying and addressing the underlying cause. In contrast, a chronic ulcer persists, potentially eroding through the muscular wall and forming fibrous tissue.
Peptic ulcers can also be...
168
Assessment of the Abdomen I: Inspection and Auscultation
405
Introduction
The abdominal examination is a cornerstone of clinical medicine, serving as a critical tool in diagnosing various gastrointestinal (GI) diseases. It involves a systematic approach that includes inspection and auscultation, each with distinct yet complementary roles in assessing the abdomen. This article will delve into these two primary methods healthcare professionals use to examine the abdomen.
Inspection of the Abdomen
The first step in any abdominal examination is inspection....
The abdominal examination is a cornerstone of clinical medicine, serving as a critical tool in diagnosing various gastrointestinal (GI) diseases. It involves a systematic approach that includes inspection and auscultation, each with distinct yet complementary roles in assessing the abdomen. This article will delve into these two primary methods healthcare professionals use to examine the abdomen.
Inspection of the Abdomen
The first step in any abdominal examination is inspection....
405
Assessment of blood pressure in brachial artery(one-step method)
591
This procedural guide systematically measures blood pressure using an oscillometric digital sphygmomanometer, emphasizing accuracy, patient safety, and comfort.
Prepare for the Procedure:
Prepare for the Procedure:
591


