评估基于互联网的干预"自拍"在单极抑郁症的参与者和对生活质量的影响:一个随机的,平行组研究
Cora Schefft1, Rico Krämer2, Raoul Haaf2
1Department of Psychiatry and Neurosciences, Charité - Universitätsmedizin Berlin, Campus Mitte, Berlin, Germany. cora.schefft@charite.de.
概括
基于互联网的认知行为疗法 (CBT) 干预措施,如Selfapy,可以改善抑郁症患者的心理和身体生活质量 (QOL). 这些数字心理健康工具为改善福祉提供了可扩展的治疗选择.
科学领域:
- 心理健康 心理健康
- 数字治疗学数字治疗学
- 心理学 心理学 心理学
背景情况:
- 抑郁症是一个重大的全球健康负担,影响社会功能,降低患者的生活质量 (QOL).
- 使用认知行为疗法 (CBT) 的基于互联网的干预措施 (IBIs) 显示出减轻症状的希望,但它们对临床抑郁症患者的质量生活的影响还未得到充分研究.
研究的目的:
- 评估基于CBT的IBI,Selfapy对被诊断患有严重抑郁症 (MDD) 或抑郁症的患者的生活质量 (QOL) 的影响.
- 为了比较治疗师指导的自我治疗,非指导的自我治疗和等待名单对照组关于QOL结果的有效性.
主要方法:
- 一个随机,并行,三臂试验,涉及401名被诊断患有抑郁症的参与者.
- 使用WHOQOL-BREF在基线,12周 (治疗后) 和24周 (随访) 评估生活质量 (QOL).
- 使用线性混合效应模型来分析QOL领域的干预效应.
主要成果:
- 与12周的对照组相比,指导和非指导的Selfapy干预措施都导致了身体和心理QOL领域的显著改善.
- 在24周的随访期间,心理质量生活的改善持续,而身体质量生活的改善却没有.
- 在研究期间,社会关系和环境领域的QOL在所有组都下降了.
- 在受引导和不受引导的自我治疗干预之间没有观察到质量生活结果的显著差异.
结论:
- 基于CBT的IBI自我治疗有效地提高了抑郁症患者的心理和身体生活质量,提供了一个可扩展的治疗解决方案.
- 观察到的质量生活改善突显了数字心理健康工具在管理抑郁症方面的潜力.
- 外部因素,如COVID-19大流行,可能影响了研究结果.
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