基于参考资料和临床试验的甲状腺癌免疫疗法的当前和未来
Ke Wang1, Ying Zhang2, Yang Xing2
1Department of Clinical Laboratory, The First Hospital of Jilin University, Jilin University, 1 Xinmin Str, Changchun, 130021, Jilin, China.
Discover oncology
|February 25, 2024
概括
甲状腺癌免疫疗法正在迅速发展,免疫检查点抑制剂对高级亚型显示有前途. 未来的研究重点是组合疗法和新的方法,如CAR-T,以获得更好的治疗结果.
科学领域:
- 内分泌学 在内分泌学.
- 在瘤学瘤学.
- 免疫治疗是一种免疫疗法.
背景情况:
- 甲状腺癌是一种显著的内分泌恶性瘤.
- 甲状腺癌的无塑性和髓性甲状腺癌存在治疗挑战.
- 目前的疗法效果有限,需要新的治疗策略.
研究的目的:
- 分析甲状腺癌免疫治疗的文献统计趋势和临床试验格局.
- 确定关键的研究领域和新兴的治疗方法.
主要方法:
- 对658篇文章和87项临床试验的图书统计分析.
- 使用Web of Science,CiteSpace和VOS Viewer进行数据库搜索.
- 对出版物和引用趋势的分析.
主要成果:
- 2018年后甲状腺癌免疫疗法研究的激增,由中国和比萨大学领导.
- 大多数试验 (55/87) 是第二阶段,重点是与免疫检查点抑制剂的联合治疗.
- 免疫检查点抑制剂是晚期骨髓和形甲状腺癌的首选治疗方案.
结论:
- 甲状腺癌免疫疗法正在快速发展,得到了参考资料和临床试验数据的支持.
- 预计将结合免疫疗法与化疗或向治疗的组合疗法.
- 新兴疗法如双特异性抗体,基于细胞因子的治疗方法和采用细胞疗法 (CAR-T,TCR-T) 显示出潜力.
关键词:
无塑性甲状腺癌 (ATC)临床试验 临床试验免疫检查点抑制剂 免疫检查点抑制剂免疫治疗是一种免疫疗法.甲状腺骨髓癌 (MTC) 是一种甲状腺癌.在PD-1/PD-L1中.科学测量分析的科学测量分析甲状腺癌是什么?甲状腺癌是什么?更多相关视频
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