聚合物-药物结合物 代肝 一种特莫佐洛米德中间体和氧化用于针对多形质母细胞瘤的增强化疗法

Ke Du1, Xiao Li2, Fude Feng1

  • 1MOE Key Laboratory of High Performance Polymer Materials and Technology, and Department of Polymer Science & Engineering, School of Chemistry & Chemical Engineering, Nanjing University, Nanjing 210023, China.

ACS applied bio materials
|February 26, 2024
PubMed
概括

这项研究开发了一种聚合物 - 药物合物 (PDC) 用于多种质母细胞瘤 (GBM) 治疗. 新型PDC同时提供Temozolomide (TMZ) 前药和氧化 (NO),显示对抗性GBM细胞的协同作用.

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