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拉敏A K97E导致NF-κB介导的炎症反应功能障碍在扩张性心肌病

Duhita Sengupta1,2, Kaushik Sengupta1,2

  • 1Biophysics and Structural Genomics Division, Saha Institute of Nuclear Physics, Kolkata, India.

Biology of the cell
|February 26, 2024
PubMed
概括

与扩张性心肌病 (DCM) 相关的特定LMNA基因突变降低了保护性NF-κB通路的调节. 这一发现为这种突变如何导致心脏病提供了新的解释.

关键词:
在 NF-κB 信号传输中.扩张性心肌病症 扩张性心肌病症表观遗传修饰 表观遗传修饰它们包括interleukins和interleukins.层 A 层 A 层

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