Jove
Visualize
联系我们
JoVE
x logofacebook logolinkedin logoyoutube logo
关于 JoVE
概览领导团队博客JoVE 帮助中心
作者
出版流程编辑委员会范围与政策同行评审常见问题投稿
图书馆员
用户评价订阅访问资源图书馆顾问委员会常见问题
研究
JoVE JournalMethods CollectionsJoVE Encyclopedia of Experiments存档
教育
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab Manual教师资源中心教师网站
使用条款与条件
隐私政策
政策

相关概念视频

Parametric Survival Analysis: Weibull and Exponential Methods01:14

Parametric Survival Analysis: Weibull and Exponential Methods

430
Parametric survival analysis models survival data by assuming a specific probability distribution for the time until an event occurs. The Weibull and exponential distributions are two of the most commonly used methods in this context, due to their versatility and relatively straightforward application.
Weibull Distribution
The Weibull distribution is a flexible model used in parametric survival analysis. It can handle both increasing and decreasing hazard rates, depending on its shape parameter...
430
Survival Curves01:18

Survival Curves

152
Survival curves are graphical representations that depict the survival experience of a population over time, offering an intuitive way to track the proportion of individuals who remain event-free at each time point. These curves are widely used in fields such as medicine, public health, and reliability engineering to visualize and compare survival probabilities across different groups or conditions.
The Kaplan-Meier estimator is the most common method for constructing survival curves. This...
152
Introduction To Survival Analysis01:18

Introduction To Survival Analysis

236
Survival analysis is a statistical method used to study time-to-event data, where the "event" might represent outcomes like death, disease relapse, system failure, or recovery. A unique feature of survival data is censoring, which occurs when the event of interest has not been observed for some individuals during the study period. This requires specialized techniques to handle incomplete data effectively.
The primary goal of survival analysis is to estimate survival time—the time...
236
Assumptions of Survival Analysis01:15

Assumptions of Survival Analysis

127
Survival models analyze the time until one or more events occur, such as death in biological organisms or failure in mechanical systems. These models are widely used across fields like medicine, biology, engineering, and public health to study time-to-event phenomena. To ensure accurate results, survival analysis relies on key assumptions and careful study design.
127
Kaplan-Meier Approach01:24

Kaplan-Meier Approach

138
The Kaplan-Meier estimator is a non-parametric method used to estimate the survival function from time-to-event data. In medical research, it is frequently employed to measure the proportion of patients surviving for a certain period after treatment. This estimator is fundamental in analyzing time-to-event data, making it indispensable in clinical trials, epidemiological studies, and reliability engineering. By estimating survival probabilities, researchers can evaluate treatment effectiveness,...
138
Actuarial Approach01:20

Actuarial Approach

78
The actuarial approach, a statistical method originally developed for life insurance risk assessment, is widely used to calculate survival rates in clinical and population studies. This method accounts for participants lost to follow-up or those who die from causes unrelated to the study, ensuring a more accurate representation of survival probabilities.
Consider the example of a high-risk surgical procedure with significant early-stage mortality. A two-year clinical study is conducted,...
78

您也可能阅读

相关文章

通过共同作者、期刊和引用图与本文相关的文章。

排序
Same author

Effectiveness of pharmacological treatment in the secondary prevention of fragility fractures: A region-wide study.

Revista espanola de geriatria y gerontologia·2026
Same author

Assessment of the ADLIFE intervention as a digital solution for patients with advanced chronic diseases: a quasi-experimental trial.

NPJ digital medicine·2026
Same author

Cost-effectiveness of fecal immunochemical testing for colorectal cancer in Mexico City: A microsimulation modeling study.

Journal of medical screening·2026
Same author

A Tutorial on Discrete Event Simulation Models Using a Cost-Effectiveness Analysis Example in R.

Medical decision making : an international journal of the Society for Medical Decision Making·2026
Same author

A Microsimulation-Based Approach for Mitigating Societal Bias in Chronic Kidney Disease Data.

Medical decision making : an international journal of the Society for Medical Decision Making·2026
Same author

Health-economic challenges for new Alzheimer's disease treatments.

The journal of prevention of Alzheimer's disease·2026

相关实验视频

Updated: Jul 2, 2025

Establishing a Competing Risk Regression Nomogram Model for Survival Data
04:57

Establishing a Competing Risk Regression Nomogram Model for Survival Data

Published on: October 23, 2020

10.2K

在模拟模型中使用特定年龄的比率进行参数生存功能的估计.

Arantzazu Arrospide1,2,3, Oliver Ibarrondo2,3,4, Rubén Blasco-Aguado5

  • 1Ministry of Health of the Basque Government, Vitoria-Gasteiz, Spain.

Medical decision making : an international journal of the Society for Medical Decision Making
|February 26, 2024
PubMed
概括

本研究提出了一种模拟事件时间的方法,用于个人级别模型的年龄特定率. 戈珀茨分布最适合数据,可以在没有单个记录的情况下准确地采样事件时间.

关键词:
卫生经济学 卫生经济学自然历史,自然历史.模拟模拟是指一个模拟模拟.进行生存分析.不确定性是一种不确定性.

更多相关视频

Measurement of Lifespan in Drosophila melanogaster
10:00

Measurement of Lifespan in Drosophila melanogaster

Published on: January 7, 2013

34.4K
Monitoring Neuronal Survival via Longitudinal Fluorescence Microscopy
07:02

Monitoring Neuronal Survival via Longitudinal Fluorescence Microscopy

Published on: January 19, 2019

6.5K

相关实验视频

Last Updated: Jul 2, 2025

Establishing a Competing Risk Regression Nomogram Model for Survival Data
04:57

Establishing a Competing Risk Regression Nomogram Model for Survival Data

Published on: October 23, 2020

10.2K
Measurement of Lifespan in Drosophila melanogaster
10:00

Measurement of Lifespan in Drosophila melanogaster

Published on: January 7, 2013

34.4K
Monitoring Neuronal Survival via Longitudinal Fluorescence Microscopy
07:02

Monitoring Neuronal Survival via Longitudinal Fluorescence Microscopy

Published on: January 19, 2019

6.5K

科学领域:

  • 流行病学 流行病学
  • 生物统计学 生物统计学
  • 卫生经济学 卫生经济学

背景情况:

  • 个人级别的模拟模型对于健康经济评估至关重要.
  • 这些模型通常需要个别患者的数据,这些数据可能并不总是可用.
  • 特定年龄的事件率通常是可访问的,但直接的个人数据缺乏.

研究的目的:

  • 描述将参数函数纳入个体级模拟模型的程序.
  • 在只有特定年龄的比率可用时,采样时间到事件数据.
  • 在缺少个人级数据的情况下,以促进模拟建模.

主要方法:

  • 参数生存分布 (Weibull,Gompertz,日志-正常,日志-逻辑) 通过回归分析使用特定年龄事件率进行参数化.
  • 最适合的分布是使用R平方统计学来选择的.
  • 选择的参数函数被应用于模拟模型中事件的随机时间分配,以西班牙的中风率为例.

主要成果:

  • 戈珀茨,韦布尔和日志常态分布表现出很好的数据适合到85岁的年龄.
  • 戈珀茨分布被确定为最适合的分布,基于它的适合性.
  • 该程序成功地将参数风险函数纳入模拟模型.

结论:

  • 为将参数风险函数集成到单个级别的模拟模型中提供了一个简单的程序.
  • 这种方法可以通过使用易于获得的特定年龄率来模拟时间到事件数据.
  • 该方法允许将参数不确定性纳入模拟,这对于概率灵敏度分析至关重要.