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Updated: Jul 2, 2025

Shotgun Proteomics Sample Processing Automated by an Open-Source Lab Robot
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使用完全自动化的蛋白质组学样本准备平台进行高通量药物标发现.

Qiong Wu1, Jiangnan Zheng1,2, Xintong Sui1

  • 1Department of Chemistry, School of Science, Southern University of Science and Technology Shenzhen 518055 China tianrj@sustech.edu.cn.

Chemical science
|February 26, 2024
PubMed
概括

这项研究引入了一种自动化工作流程,用于使用单温度热蛋白质组概况 (TPP) 和质谱 (MS) 发现药物标. 该方法显著提高了识别药物标和非标的吞吐量,解决了药物开发中的低效率问题.

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Proteomics01:33

Proteomics

A proteome is the entire set of proteins that a cell type produces. We can study proteomes using the knowledge of genomes because genes code for mRNAs, and the mRNAs encode proteins. Although mRNA analysis is a step in the right direction, not all mRNAs are translated into proteins.
Proteomics is the study of proteomes' function. It involves the large-scale systematic study of the proteome to denote the protein complement expressed by a genome. Scientist Mark Wilkins coined the term...
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