心力衰竭风险中的农村和种族:来自南方社区队列研究的见解
1Aswan Heart Centre (AHC), Aswan, Egypt.
Global cardiology science & practice
|February 26, 2024
概括
农村人口面临心力衰竭 (HF) 的更高发病率,特别是在黑人男性和女性中. 这种心力衰竭风险增加与农村生活有关,突出了心血管疾病结果的差异.
科学领域:
- 公共卫生 公共卫生
- 心血管流行病学心血管流行病学
- 健康差距 研究 研究 研究 研究
背景情况:
- 包括心血管疾病 (CVD) 和心力衰竭 (HF) 在内的健康结果的农村和城市差异已得到充分记录,但尚未完全理解.
- 导致这些差异的因素需要进一步调查,以告知有针对性的公共卫生干预措施.
研究的目的:
- 调查农村生活与心力衰竭 (HF) 发病率之间的联系.
- 为了检查这种联系如何因种族和性别而异.
主要方法:
- 分析了来自南部社区队列研究 (SCCS) 的27,115名参与者的数据.
- 预期追踪平均13年以确定HF事件.
- 根据年龄调整的发病率和危险比率 (HR) 被计算出来,以评估与农村居住相关的HF风险,按种族和性别分层.
主要成果:
- 与城市参与者相比,农村参与者呈现出更高的HF年龄调整发病率 (36.5对29.6每1000人年).
- 农村黑人男性 (HR,1.34),农村黑人女性 (HR,1.18) 和农村白人女性 (HR,1.22) 的高血压风险与农村生活相关.
- 在农村白人男性中,农村和HF风险之间没有显著的关联 (HR,0.97).
结论:
- 农村人口患心力衰竭 (HF) 的发病率增加,尤其是女性和黑人男性.
- 这种高风险似乎独立于个人层面的生物学,行为和社会文化因素.
- 需要进一步的研究,以了解农村和城市高频差异的根本原因,并指导有效的预防策略.
相关概念视频
01:30Factors Influencing Heart Rate
2.6K
The heart rate, or pulse rate, is a vital indicator of cardiovascular health. It reflects the number of times the heart beats per minute. Various physiological and environmental factors influence heart rate, increasing or decreasing cardiac output. Understanding these factors is crucial for assessing heart function and identifying potential health issues.
Let us explore the significant factors affecting heart rate, including age, body temperature, posture, acute pain, chemical influences,...
Let us explore the significant factors affecting heart rate, including age, body temperature, posture, acute pain, chemical influences,...
2.6K
01:26Heart Failure Drugs: Inhibitors of Renin-Angiotensin System
431
The activation of the sympathetic nervous system and the renin-angiotensin-aldosterone system (RAAS) contributes to cardiac remodeling, and inhibiting the RAAS is a pharmacological target in heart failure management. As a result, neurohumoral modulation is a crucial treatment principle for managing heart failure. This approach involves using medications like ACE inhibitors (ACEIs), angiotensin receptor blockers (ARBs), β-blockers, mineralocorticoid receptor antagonists (MRAs), and neutral...
431
01:17Pathophysiology of Heart Failure
1.6K
Heart failure (HF) is a progressive syndrome involving ventricles that leads to inadequate cardiac output. It can be classified based on location and output or ejection fraction. Ejection fraction (EF) is an essential measurement in the diagnosis and surveillance of HF. Reduced EF corresponds to systolic heart failure (HFrEF). However, HF with preserved ejection fraction (HFpEF) is becoming increasingly prevalent. Also known as diastolic HF, this form of HF is related to aging. The...
1.6K
01:17Ischemic Heart Disease: Overview
1.3K
Ischemic heart disease occurs when the heart's blood supply dwindles, causing an ominous lack of oxygen and nutrients. This deficiency, stemming from reduced or obstructed blood flow, spells danger, leading to heart muscle damage and dysfunction.
Atherosclerosis, the primary malefactor, orchestrates this dangerous condition. It manifests as the accumulation of fatty deposits, akin to insidious plaques, within arterial walls. As time elapses, these plaques metamorphose, hardening and...
Atherosclerosis, the primary malefactor, orchestrates this dangerous condition. It manifests as the accumulation of fatty deposits, akin to insidious plaques, within arterial walls. As time elapses, these plaques metamorphose, hardening and...
1.3K
01:22Heart Failure Drugs: β-Blockers
340
β-adrenergic antagonists, commonly known as β-blockers, block the effects of sympathetic neurotransmitters such as noradrenaline (NA) and adrenaline (ADR). They have several beneficial effects in heart failure treatment. They reduce heart rate, the force of contraction, and cardiac muscle relaxation. They also slow the atrial-ventricular conduction rate and raise the threshold for arrhythmias. The concentration of β-blockers determines their effects on bronchodilation,...
340
01:22Heart Failure Drugs: Diuretics
381
Heart failure and kidney perfusion are interconnected in a complex way. Reduced renal perfusion and venous congestion are two significant factors that contribute to renal dysfunction in heart failure. The kidneys, primarily responsible for fluid balance in the body, are adversely affected due to compromised cardiac output and increased venous pressure. In response to reduced renal perfusion, the kidneys activate neurohumoral mechanisms to restore balance. However, these mechanisms can be...
381