通过卷积神经网络在医院间检测中度和晚期阿尔茨海默病
Carlos Roncero-Parra1, Alfonso Parreño-Torres2, Roberto Sánchez-Reolid3
1Departamento de Sistemas Informáticos, Universidad de Castilla-La Mancha, Campus Universitario, Albacete, 02071, Spain.
Heliyon
|February 26, 2024
概括
机器学习和深度学习分析脑电图 (EEG) 数据,以分类阿尔茨海默氏症 (AD) 阶段. 一个卷积神经网络 (CNN) 在区分中度和高级痴呆症方面取得了97.45%的准确性.
科学领域:
- 神经科学是一个神经科学.
- 人工智能的人工智能
- 医学诊断 医学诊断 医学诊断
背景情况:
- 电脑电图 (EEG) 是确定神经疾病的关键工具.
- 阿尔茨海默病 (AD) 的诊断和分期对于患者的护理至关重要.
- 机器学习 (ML) 和深度学习 (DL) 为复杂的生物数据提供了先进的分析能力.
研究的目的:
- 用EEG数据评估ML和DL方法来分类阿尔茨海默病 (AD) 严重程度.
- 为了比较各种ML/DL模型在区分中度阿尔茨海默氏症痴呆症 (ADM) 和高级阿尔茨海默氏症痴呆症 (ADA) 的性能.
- 确定最有效的DL方法来分析EEG信号用于AD分期.
主要方法:
- 在10年内利用了来自5家医院的668名志愿者的综合数据集.
- 应用并将多个机器学习和深度学习模型与EEG数据进行比较.
- 专注于一个卷积神经网络 (CNN) 深度学习模型,因为它具有特征提取能力.
主要成果:
- 卷积神经网络 (CNN) 深度学习模型表现出卓越的性能.
- 在中度阿尔茨海默氏症痴呆症 (ADM) 中获得了97.45%的分类准确度.
- 在高级阿尔茨海默氏症痴呆症 (ADA) 方面获得了97.03%的分类准确度.
结论:
- 深度学习,特别是CNN,有效地分析了AD分期的时间域EEG特征.
- 拟议的CNN模型显著减少了可学习参数和数据冗余.
- 这种方法显示出使用EEG准确和高效地分类阿尔茨海默病的巨大潜力.
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