对有炎症性肠病的老年人进行管理考虑
Ellen Axenfeld1, Seymour Katz1,2, Adam S Faye1,2
1Division of Gastroenterology and Hepatology, Department of Medicine, New York University Langone Health, New York, New York.
Gastroenterology & hepatology
|February 26, 2024
概括
在老年人中炎症性肠病 (IBD) 的流行率不断上升,需要量身定制的诊断和管理策略. 整合诸如脆弱性之类的生物年龄指标可以改善风险分层和患者的治疗结果.
科学领域:
- 胃肠病学 胃肠病学
- 老年病的医生 老年病的医生
- 内部医学 内部医学
背景情况:
- 在老年人群中,炎症性肠病 (IBD) 的患病率越来越高,这带来了独特的诊断和管理挑战.
- 与年轻人相比,患有IBD的老年人面临更高的不良事件风险.
- 目前的数据表明疾病活动,而不是治疗,是老年IBD患者不良结果的关键驱动因素.
研究的目的:
- 审查患有炎症性肠病 (IBD) 的老年人管理方面的考虑.
- 通过了解表型差异和症状与其他疾病重叠,突出及时诊断的重要性.
- 倡导将生物年龄测量措施纳入临床实践,以改善风险分层.
主要方法:
- 对老年人炎症性肠病 (IBD) 的当前文献的综述.
- 对影响诊断和管理因素的分析.
- 讨论生物年龄标志物 (脆弱性,) 在风险评估中的作用.
主要成果:
- 在老年人中及时诊断IBD需要识别不同的表型和重叠的症状.
- 持续的疾病活动,而不是治疗,显著推动IBD老年患者的不良临床结果.
- 早期和有效的治疗对于改善这一群体的生活质量至关重要.
结论:
- 仅仅是时间学年龄对于IBD的老年人进行医疗决策是不够的.
- 在风险分层工具中整合生物年龄测量,如脆弱性和肉症,是必不可少的.
- 采用基于生物年龄的方法可以加强临床管理,改善老年IBD患者的治疗结果.
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