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人类胎儿大脑皮层扩张的分子特征

G Ball^1,2, S Oldham¹, V Kyriakopoulou^3,4

¹Developmental Imaging, Murdoch Children's Research Institute, Melbourne, Australia.

bioRxiv : the preprint server for biology

|February 26, 2024

概括

新的μBrain图谱揭示了基因表达如何在人类妊娠期间驱动差异性大脑扩张. 这将产前发育与认知障碍联系在一起,为大脑生长提供了洞察力.

科学领域:

神经科学是一个神经科学.
发展生物学发展生物学
计算生物学计算生物学

背景情况:

人类妊娠的第三个三个月看到快速的大脑生长和在发育中的皮质中的分子多样性.
了解分子差异如何在妊娠晚期驱动差异性皮质扩张至关重要.

结论:

在神经发生的时间和产前新皮层扩张率之间存在空间合.
大脑图谱有助于绘制不同尺度和系统的早期大脑发育的地图.
研究结果将产前大脑发育模式与具有认知后果的遗传疾病联系起来.

关键词:

亚特兰大亚特兰大亚特兰大亚特兰大皮层皮层皮层一个胎儿的胎儿.人类大脑发育人类大脑发育翻译学翻译学翻译学翻译学

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