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相关概念视频

CNS Stimulants: Psychedelic Agents01:22

CNS Stimulants: Psychedelic Agents

Hallucinogens, also known as psychedelic drugs, are a class of substances known for their ability to alter perception, cognition, and emotions. Despite their profound effects on the mind, these drugs are non-addictive, setting them apart from many other abused substances. The mechanism of action of these drugs lies in their impact on the 5-HT2A receptor in the brain. Upon activation, this receptor couples to Gq-type G proteins, triggering a cascade that releases intracellular calcium. This...
Hallucinogens and Psychedelics01:27

Hallucinogens and Psychedelics

Hallucinogens are psychoactive substances that profoundly alter perceptual experiences, generating unreal visual and sensory images. Often referred to as psychedelic drugs — a term derived from the Greek words "psyche" (mind) and "delos" (revealing) — these substances include marijuana and lysergic acid diethylamide (LSD), among others. These drugs vary in intensity and effects.
Marijuana, derived from the dried leaves and flowers of the hemp plant, contains delta-9-tetrahydrocannabinol (THC)...

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相关实验视频

Updated: Jul 9, 2026

Electroconvulsive Seizures in Rats and Fractionation of Their Hippocampi to Examine Seizure-induced Changes in Postsynaptic Density Proteins
09:07

Electroconvulsive Seizures in Rats and Fractionation of Their Hippocampi to Examine Seizure-induced Changes in Postsynaptic Density Proteins

Published on: August 15, 2017

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松素诱导了大鼠皮质功能网络组织的剂量依赖性变化.

Brian H Silverstein1,2, Nicholas Kolbman1,2,3, Amanda Nelson1

  • 1Department of Anesthesiology, University of Michigan, Ann Arbor, Michigan 48109, USA.

bioRxiv : the preprint server for biology
|February 26, 2024
PubMed
概括

松素改变了大鼠的大脑网络动态,因剂量而异地破坏了太-玛合并增加了高频连接. 网络组织中的这些变化可能意味着psilocybin诱导的改变意识状态.

科学领域:

  • 神经科学是一个神经科学.
  • 心理药理学 心理药理学
  • 计算精神病学是一种计算精神病学.
关键词:
高马振荡的高马振荡.阶段幅度合器相位幅度合器这种药物是psilocybin.迷幻药物 迷幻药物鼠标 鼠标 鼠标 鼠标有权重的阶段滞后指数.

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Recording and Modulation of Epileptiform Activity in Rodent Brain Slices Coupled to Microelectrode Arrays
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Ex Vivo Optogenetic Interrogation of Long-Range Synaptic Transmission and Plasticity from Medial Prefrontal Cortex to Lateral Entorhinal Cortex
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相关实验视频

Last Updated: Jul 9, 2026

Electroconvulsive Seizures in Rats and Fractionation of Their Hippocampi to Examine Seizure-induced Changes in Postsynaptic Density Proteins
09:07

Electroconvulsive Seizures in Rats and Fractionation of Their Hippocampi to Examine Seizure-induced Changes in Postsynaptic Density Proteins

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Recording and Modulation of Epileptiform Activity in Rodent Brain Slices Coupled to Microelectrode Arrays
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Ex Vivo Optogenetic Interrogation of Long-Range Synaptic Transmission and Plasticity from Medial Prefrontal Cortex to Lateral Entorhinal Cortex
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背景情况:

  • псилоцибин诱导意识的改变状态,需要动物模型来研究大脑网络动态.
  • 以前使用电脑电图 (EEG) 的动物研究缺乏空间分辨率来进行网络分析,并且仅限于较低的马频率.

结论:

  • 西可显著改变大脑网络组织,以剂量依赖的方式.
  • 高频网络活动,独立于泰达阶段,似乎对于西诱导的改变状态至关重要.
  • 这项研究为了解动物模型中的迷幻机制提供了基础.