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Updated: Jul 2, 2025

Investigation of Macrophage Polarization Using Bone Marrow Derived Macrophages
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葡萄糖皮质体和IL4驱动的巨细胞编程之间的表观基因组和功能融合机制

Dinesh K Deochand1, Marija Dacic1,2, Michael J Bale3,4

  • 1Hospital for Special Surgery Research Institute, The David Rosenzweig Genomics Center, New York, NY, USA.

bioRxiv : the preprint server for biology
|February 26, 2024
PubMed
概括

葡萄糖皮质类药物和介质素-4通过调节基因表达和染色蛋白来诱导类似的巨细胞状态. 辅因子GRIP1集成这些信号,影响巨细胞功能和组织修复.

关键词:
恒常性巨细胞编程 恒常性巨细胞编程染色体和表观基因组学增强景观 增强景观葡萄糖皮质类受体受体克鲁佩尔之类的因素4组织修复和炎症.转录规则 转录规则 转录规则

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