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Updated: Jul 2, 2025

A Restriction Enzyme Based Cloning Method to Assess the In vitro Replication Capacity of HIV-1 Subtype C Gag-MJ4 Chimeric Viruses
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轻微的HIV特异性选择力覆盖自然的CD4+T细胞动态解释了HIV储存细胞的克隆性和衰变动态

Daniel B Reeves, Danielle N Rigau, Arianna Romero

    medRxiv : the preprint server for health sciences
    |February 26, 2024
    PubMed
    概括

    在接受抗逆转录病毒疗法 (ART) 的艾滋病毒感染者 (PWH) 中,艾滋病毒的持续性在很大程度上是由自然记忆CD4+T细胞动态驱动的. 然而,特定于艾滋病毒的负选择也有助于清除一些完整和有缺陷的前病毒.

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