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Updated: Jul 2, 2025

Tumor Transplantation for Assessing the Dynamics of Tumor-Infiltrating CD8+ T Cells in Mice
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破坏CD38驱动的T细胞功能障碍恢复了对癌症免疫疗法的敏感性

Or-Yam Revach1,2,3, Angelina M Cicerchia1, Ofir Shorer4

  • 1Mass General Cancer Center, Krantz Family Center for Cancer Research, Department of Medicine, Massachusetts General Hospital, Boston, MA, USA.

bioRxiv : the preprint server for biology
|February 26, 2024
PubMed
概括

向与T细胞枯竭相关的酶CD38可以克服对癌症免疫疗法的抵抗力. 阻断CD38恢复T细胞功能,并增强对黑色素瘤免疫检查点阻断的反应.

关键词:
3D微流体培养方法CD38 CD38 CD38 CD38 CD38 CD38 CD38 CD38 CD38 CD38 CD38 CD38 CD38 CD38它们是NAD+NAD+NAD.在PD-1中使用PD-1.T细胞耗尽的情况.细胞因子 细胞因子免疫疗法 免疫疗法器官类型的瘤球形状物

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