在长期护理机构中对SARS-CoV-2的环境采样:从试点研究中吸取教训
Rachel Kwiatkowska1,2,3, Nicola Yaxley4, Ginny Moore4
1Population Health Sciences, Bristol Medical School, University of Bristol, Bristol, UK.
Wellcome open research
|February 26, 2024
概括
环境监测检测到长期护理设施 (LTCF) 中的SARS-CoV-2RNA,包括高层表面. 这表明环境采样可能有助于在这些脆弱环境中预防和控制感染.
科学领域:
- 预防和控制感染的预防和控制.
- 环境微生物学 环境微生物学
- 流行病学 流行病学
背景情况:
- 长期护理设施 (LTCF) 是SARS-CoV-2传播的高风险环境.
- 居住在LTCF的居民特别容易受到感染的严重后果的影响.
- 环境监测为早期病原体检测和控制措施提供信息提供了一个潜在的战略.
研究的目的:
- 在疫情爆发期间在LTCF试点环境采样SARS-CoV-2.
- 评估在各种表面上检测SARS-CoV-2RNA的可行性和实用性.
- 收集关于LTCF基础设施,行为和感染控制措施的上下文数据.
主要方法:
- 在英格兰西南部的三个LTCF参与了试点研究.
- 调查人员为SARS-CoV-2 RNA扫描了常见的接触点和升高的表面 (>1.5m).
- 为了背景,收集了临床,流行病学和IPC数据.
主要成果:
- 在样本LTCF中检测到SARS-CoV-2RNA,感染居民的房间中阳性率更高.
- 与常见接触点相比,高处表面的比重较大,测试结果呈阳性.
- 在一个有加强感染预防和控制 (IPC) 措施的设施中观察到较低的污染水平.
结论:
- 在疫情爆发期间,SARS-CoV-2 RNA可在LTCF内经常触摸和升高的表面上检测到.
- 环境采样对LTCF的感染监测有希望.
- 需要进一步的研究来评估这种方法对IPC的可行性和有用性.
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