关于动物中风心脏病发作量的数据集:MRI和组织学方法的比较
Rebecca Z Weber1,2, Davide Bernardoni3, Nora H Rentsch1,2
1Institute for Regenerative Medicine, University of Zurich, Schlieren 8952, Switzerland.
Data in brief
|February 26, 2024
概括
这项研究介绍了光血栓性中风后的小鼠大脑图像,比较磁共振成像 (MRI) 和组织学,以评估急性和慢性阶段的心脏病发作. 该数据集有助于估计中风体积和技术比较.
科学领域:
- 神经科学是一个神经科学.
- 医疗成像医学成像
- 脑卒中研究 脑卒中研究
背景情况:
- 光血栓性中风模型对于研究脑损伤至关重要.
- 准确的心脏病发作体积评估对于中风研究至关重要.
- 通过比较神经成像和组织学技术,可以了解中风病理学.
研究的目的:
- 为了提供一组数据集的小鼠大脑与光血栓性中风.
- 为了能够比较MRI和组织学方法用于心脏病发作量化.
- 支持对中风体积估计技术的研究.
主要方法:
- 整个大脑的活体磁共振成像 (MRI) 用于对脑中风后的小鼠大脑进行成像.
- 冠状腺组织学切口 (40微米) 用NeuroTrace进行染色.
- 在急性 (3天) 和慢性 (28天) 时间点评估了心脏病发作区域和体积.
主要成果:
- 数据集包括MRI和小鼠大脑的组织学图像.
- 内心评估是在两个不同的时间框架中进行的.
- 数据允许直接比较成像方式.
结论:
- 该数据集对于验证中风体积估计方法非常有价值.
- 它有助于在中风研究中比较MRI和组织学技术.
- 这个资源支持进一步调查传感运动皮质中风.
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