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提高长距离外围神经缺陷损伤的再生和修复,使用连续微电流电神经刺激

Junjie Kong1, Cheng Teng1, Fenglan Liu1

  • 1Key Laboratory of Neuroregeneration of Jiangsu and Ministry of Education, Affiliated Hospital and Medical School, Co-innovation Center of Neuroregeneration, Nantong University, Nantong, China.

Frontiers in neuroscience
|February 26, 2024
PubMed
概括

连续微电流电神经刺激 (cMENS) 通过促进施万细胞活动和神经营养因子分泌来增强外围神经的修复. 这种辅助疗法改善了功能恢复,并减少了老鼠坐骨神经损伤模型中的肌肉缩.

关键词:
Schwann 细胞的活动.连续微电流电动神经刺激电动神经刺激.功能恢复恢复的功能恢复.长距离神经缺陷 长距离神经缺陷周围神经受伤的情况组织工程是组织工程.

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In the CNS, neurogenesis, the birth of new neurons from stem cells, is limited to the hippocampus in adults. In other regions of the brain and spinal cord, neurogenesis is almost non-existent due to inhibitory influences from neuroglia, especially oligodendrocytes, and the absence of growth-stimulating cues. The myelin produced by oligodendrocytes in the CNS inhibits neuronal regeneration. Furthermore, astrocytes proliferate rapidly after neuronal damage, forming scar tissue that physically...
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